rnix 82 50 LC 066 ppm lethal exposure of lead acetate and vitamin C on -Effects of sub histopathology of gonads of Local quail in Misurata

Abstract

The reproductive organs are essential not only for the life of the individual but also for the survival and development of the species, where thetoxic effect of lead on reproduction is widespread and is harmful to every part of the body, especially the female and male reproductive system, and may damage it to the destruction of reproductive organs. The present study aimed to investigate the toxic effects of lead acetate exposure in Local quail (Coturnix sp.) and its amelioration through vitamin C (60 mg-1). A total number of 48 specimens were collected from local market in Misurata city ware chronically exposed to lead acetate for 21 days exposed at a dose of LC50 value 600 ppm. In the current study, a Rotary-microtome was used to histological sections. Results showed that some structural changes were observed in gonads of female and male quail, where the histological examination showed in the ovarian of the quail exposed to lead acetate, degeneration and damage in the ovarian stromal tissue. Furthermore, The appearance of the walls of the vesicles were irregular. While testicular tissue of experimental study exposure to sublethal concentrations of lead acetate caused vascular, interstitial and tubular histological alterations that, interstitial fibrosis, vacuoles, Leydig cell degeneration, thickening of the seminiferous tubular basement membrane and congestion in blood vessels. the histological findings of this study indicate that chronic exposure to lead produces significant histological alterations in the ovarian and testes, also results clearly showed that vitamin C attenuated the deleterious impact of lead on the reproductive system.