LAPAROSCOPIC OVARIAN DRILLING TREATMENT OPTION FOR POLYCYSTIC OVARY AND INFERTILITY

Abstract

To find out the effectiveness of laparoscopic ovarian drilling (LOD) in patients clinically and radiologically diagnosed as Polycystic Ovarian Syndrome (PCOS) suffering from infertility and to find out factors that may predict the
outcome of LOD. This prospective study included 186 patients with anovulatory infertility due to PCOS who underwent LOD during the period from January 1st 2007 to December 31st 2008. Diagnosis was made according to the
European Society of Human Reproduction and Embryology (ESHRE) criteria for PCOS. Body Mass Index (BMI),
serum Testosterone level and serum LH was taken from the patients. All patients were followed up till they got
pregnant or for a period of 12 months after the procedure. Out of 186 patients, 102 (55%) conceived after long term
infertility ranged from 3-15 years, Antenatal complications were not significant as there was 1 twins pregnancy, 3
miscarriages and 1 ectopic pregnancy, Patients with Body Mass Index ≥ 35 kg/m2
and serum testosterone level ≥ 4.5
nmol/l seems to be poor responders for LOD, meanwhile those with Serum LH level > 10 IU/L appears to be associated with higher pregnancy rate after LOD. LOD gave good fertility rates in patients with PCOS in which medical
ovulation induction failed, marked obesity and hyperandrogenism are a marked predictor for resistance to LOD,
while high level of LH predicts to a higher probability of pregnancy.