Misurata Medical Sciences Journal (MMSJ)

About the Journal
Misurata Medical Sciences Journal (MMSJ) is an open-access journal, published biannually by Misurata University. All submissions......More

Editor in Chief .. Prof. Yassen Ahmed Aboushahma

On This Issue...


MANAGEMENT OPTION OF CHILDHOOD EXOSEVIATION

Noora Alzain
Yassen Aboushahma
Intermittent exotropia is the most common form of divergent strabismus. Treatment is indicated with increasing tropia phase to preserve or restore binocular function and restore/reconstruct normal ocular alignment. While medical treatment is sometimes helpful for temporary relief, surgical therapy is the preferred definitive treatment modality by most pediatric ophthalmologists and astrobiologists. Congenital exotropia is rarely associated with amblyopia. The treatment of choice in this condition is also surgical. Sensory exotropia is most often acquired after monocular visual loss. The preferred treatment is surgical recession/resection on the impaired eye. Convergence insufficiency is usually not diagnosed until the teenage years or later, and it is best approached non-surgically with convergence exercises. In this article, we review the current literature and practice on the diagnosis and management of exotropia with emphasis on intermittent exotropia..


Date Published : 2024-04-29
10

PREVALENCE AND ANTIBIOTIC SUSCEPTIBILITY OF COMMON URINARY BACTERIAL ISOLATES FROM OUT-PATIENTS IN MISRATA, LIBYA

Abdallah Abdallah Mahjoub
Aisha Mohammed Elshwehdi
Alaa Milad Bakeer
Objective: To investigate the prevalence and antibiotic susceptibility of bacterial strains isolated from urine specimen of out-patients with UTI in Misrata region, Libya. Method: A retrospective cross-sectional study was conducted by reviewing the results of microbiological culture and sensitivity tests performed in Alnoor Medical Laboratory in Misurata city from the first of January 2021 to 31th of December 2021. Data were processed and analyzed by IBM SPSS statistical version 25. A p value of less than 0.05 was considered as statistically significant. Results: Three hundred (300) urine samples of 300 UTI patients were positive for pathogenic bacteria. S. aureus was the predominate isolate, representing 49.33% of all bacterial isolates, followed by E. Coli (26.33%), Klebsiella Spp. (10.34%), Streptococcus Spp. (7.66%), Pseudomonas Spp. (2.66%), Proteus Spp. (2.34%), and Acinobacter Spp. (1.34%). The age of the patients has a significant effect on the distribution of uropath.


Date Published : 2024-04-30
10

A STUDY OF PHYTOCHEMICAL SCREENING AND ANTICONVULSANT ACTIVITY OF PALM LEAVES PHOENIX DACTYLIFERA

Emhemed M Abukhattala
Maher A. Matar
Malak M. Keiba3
The present study aimed to evaluate the anticonvulsant activity of leaves plant extract of phoenix dactylifera L. using PTZ-induced seizure models. The leaves of date-palm was subjected to extraction in methanol (99.9%). The phytochemical screening of the extract revealed the presence the alkaloids, falvonoids, glycosides, saponin, steroids, tannins, and gum. The methanolic activity of the extract of the leaves of date-palm was observed for their anticonvulsant activity induced by pentylenetetrazole test using Albino Westar rats. The extract in doses (100, 200, 400 mg/kg, intraperitoneal) for 5 successive days. Complete protection against Tonic–clonic convulsion and mortality were observed. We concluded that phoenix dactilifera leaves pose anticonvulsant properties and further investigation and phytochemical screening are needed to find out the much action. .


Date Published : 2024-04-30
9

TRANEXAMIC VERSUS KLIGMAN IN MELASMA TREATMENT

Khaled Gharib
Amany Nassar
Fathi Essnusi Elkasah
Mohamed Hussein AbouHadeed
Melasma is a common dermatological condition that may presents a great therapeutic challenge to treat. The specific aim of the present study was to evaluate the efficacy and safety of topical tranexamic Acid (TA 3 %) loaded chitosan microparticles (TA-CsMPs) as compared with modified Kligman’s formula. A total 24 females with melasma in our nonrandomized comparison study were classified into 2 groups. Group (I) females advised to apply topical 3 % TA-Cs microgel twice daily, while group (II) was received Kligman regimen once daily at night. A modified Melasma Area Severity Index (mMASI) score was used to evaluate patients clinically once weekly for 6 weeks and followed up for 3 more months after treatment completion. Dermal type of melasma, with a lateral or centro-facial pattern of distribution and Fitzpatrick type III was found mostly in patients. The m-MASI score was significantly lower in comparison to the baseline in both investigated groups. Beside the adverse reactio.


Date Published : 2024-04-30
9

THE EFFECT OF BODY MASS INDEX, AND VITAMIN D LEVEL ON ACNE IN FEMALE PATIENTS IN MISRATA CITY

Mohammed Omar Eltaweel
Hawa Omar Eltaweel
Acne is a chronic inflammatory disease that affects the pilosebaceous unit, it is considered as one of the most common skin diseases worldwide, especially among adolescent population. The pathogenesis of acne is largely multifactorial and is still not fully understood. In contrast to our knowledge of the genetic and hormonal role in the pathogenesis of acne, there is uncertainty regarding other factors, including diet, body mass index and vitamin D. Studies of the role of these factors in the pathogenesis of acne have shown conflicting and inconclusive results. This study aimed to know the effect of body mass index, and vitamin D level on acne vulgaris, and their association with acne severity through a representative sample of female acne patients in Misrata city. A prospective study, a total of 129 acne vulgaris female patients and 47 matched healthy subjects as controls have been enrolled in this study. To collect data a self-made questionnaire was designed. The collected.


Date Published : 2024-04-30
9

Detection of Typical and Blast Cells in Acute and Chronic Leukaemia Using the Manual Method and Hematology Analyzer BC-720

Emhemed M Abukhattala
Maher A. Matar
Malak M. Keiba
Introduction: Diagnosing Leukaemia requires precise identification of atypical white blood cells. This research aims to compare the effectiveness of the BC-720 analyzer and manual microscopy in identifying blast and typical cells in both acute and chronic Leukaemia. Manual microscopy and the BC-720 analyzer were used to investigate differential white blood cell counts from 68 Leukaemia patients and 18 controls. Sensitivity and error rates for detecting abnormal cells were evaluated. The manual approach had a recognition loss of 12%, but successfully identified 47.1% of cases. The BC-720 identified 52.9% of cases, with higher detection rates in chronic patients (41.2%) and control cases (5.9%). In acute cases, the detection loss was 8.0% lower. Both methods showed advantages and limitations. The BC-720 demonstrated higher detection rates for abnormal cells, particularly in acute Leukaemia, and lower recognition losses compared to manual microscopy. It can aid in more accurate.


Date Published : 2024-04-30
9

LANGERHANS CELL HISTIOCYTOSIS SINGLE SYSTEM MULTIFOCAL BONE INVOLVEMENT A CASE REPORT WITH REVIEW OF THE LITERATURE

Sarah M. Alfaqaih
Alya S. Elshahoubi
Fatima A. Eltawahny
Langerhans cell histiocytosis is a rare disease with abnormal accumulations of Langerhans cells in different body organs. The skeletal system is a commonly the affected site in pediatric populations, and treatment modalities are varied according to the affected sites and the extent of the disease. We present the clinical details of a 12- year-old girl patient diagnosed with single-system multifocal skeletal involvement (SS-LCH). The scans of her spine revealed a full collapse fracture of the seventh thoracic vertebral body, along with other lytic lesions affecting the vertebrae at levels D2, D5, and L1. The patient had chemotherapeutic treatment in accordance with the established guidelines for Langerhans cell histiocytosis. The radiographic features alone may evoke a higher level of suspicion for Langerhans cell histiocytosis (LCH), but they lack sufficient diagnostic capacity on their own. Histopathological examinations are necessary to definitively establish or rule out a.


Date Published : 2024-04-30
9

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