Soil contaminated with helminth eggs and protozoan cysts are potential sources of infection have been recognized as an important public health problem. The aim of the present study was to screen soil samples collected from 14 different regions of house land in the Misurata city in the presence of soil-transmitted helminth eggs, cysts, and oocysts of protozoans. 252 soil samples was collected around houses during summer 2016 and winter 2017 and the samples were kept in sterile plastic bags and transported to the laboratory. The samples were examined using the centrifugal sedimentation method to identify and determine egg/cyst counts per gram for each parasite. From the obtained result, contamination rate was 75.8%, with significant differences (P 0.01) of density of infection with the season. Moreover, the results illustrated significant differences (P 0.01) between the contamination rate with parasite and soil pH. The total contamination rate with helminth eggs were 58.6% and protozoan cysts (88%), with significant differences (P 0.01) between the contamination rates of helminth eggs and protozoan cysts at the same season. Four genera of nematodes with oocaa eggs (73%) the highest, followed by scais (16.1%), Stonyoides spp. Larvae (11.6%) and ichis (0.9%), In addition, two genera of cestodes with Hyenoepis nana (14.2%) and Taenia spp (10.7%). Four genera of protozoan cysts and oocysts were detected (ntaoeba histoytica, Coccidian oocysts, iadia spp and ntaoeba coli). The study highlighted the public health importance of a polluted environment in houses, especially when not properly prepared. The results also indicated the presence of these parasites in the soil, hence, improper disposal of human and animal faces, insufficient supplies of potable water, as well as poor personal hygiene are the key factors for the transmission of these parasites.