This work introduces a new palladium catalyst based on Methyl (Z)-(4-oxopent-2-en- 2-yl)glycinate as multi-dentate ligand and its utilization in the Heck-Mizoroki coupling reaction between acrylamide as an electron deficient alkene and iodobenzene as example of aryl halide to form the corresponding cinnamamide in good to excellent yields. The highest turnover number (TON) and turnover frequency (TOF) of the catalytic system of this reaction were reached to 7067 and 1413, respectively.