A STUDY OF PHYTOCHEMICAL SCREENING AND ANTICONVULSANT ACTIVITY OF PALM LEAVES PHOENIX DACTYLIFERA

Abstract

The present study aimed to evaluate the anticonvulsant activity of leaves plant extract
of phoenix dactylifera L. using PTZ-induced seizure models. The leaves of date-palm
was subjected to extraction in methanol (99.9%). The phytochemical screening of the
extract revealed the presence the alkaloids, falvonoids, glycosides, saponin, steroids,
tannins, and gum. The methanolic activity of the extract of the leaves of date-palm
was observed for their anticonvulsant activity induced by pentylenetetrazole test using
Albino Westar rats. The extract in doses (100, 200, 400 mg/kg, intraperitoneal) for 5
successive days. Complete protection against Tonic–clonic convulsion and mortality
were observed. We concluded that phoenix dactilifera leaves pose anticonvulsant
properties and further investigation and phytochemical screening are needed to find
out the much action.