IN VITRO COMPARATIVE QUALITY ASSESSMENT OF FUROSEMIDE BRANDS MARKETED IN MISURATA CITY

Ali Rafieda
Choosing the proper drug product is becoming increasingly complicated for health professionals and patients due to the abundance of generic brands in the local drug market. This study aimed to evaluate the different physicochemical parameters of furosemide (FSM) tablets from various manufacturers using in vitro tests to minimize health risk factors and maximize the safety of consumers. Four brands (X1, X2, X3, X4) of furosemide tablets were evaluated using both official and unofficial in vitro Quality control tests, including both official and unofficial methods: visual inspection, uniformity of weight, thickness and diameter test, hardness test, friability test, disintegration test, dissolution test, and uniformity content assay. The results showed that all four brands of the (FSM) tablets are meet the British Pharmacopeia (BP) and United State Pharmacopeia (USP) standard specifications for in vitro evaluation Quality control tests. Physicians can recommend any of these four products .

Tonsillitis Index, recommendation for tonsillectomy in recurrent/chronic tonsillitis

Khalid Bayou
Mohammed Patel
A prospective study was conducted on 57 patients. The aim of this study is to find out the concept of Tonsillitis Index as a clinical decision-making as a guide and indicator to recommend tonsillectomy in patients with recurrent/chronic tonsillitis. Data were collected, including the disease history data, based on the evaluation of the severity of the recurrent tonsillitis and length of morbidity period. Microbiology reports of tonsillar surface swabs, tonsil core specimens and blood culture reports were collected. (Tonsillitis Index) to investigate whether there is a relationship between the disease history of recurrent /chronic tonsillitis and the macroscopic signs of sclerotic process in tonsils were evaluated. The statistical analysis of the study showed good correlation between tonsillitis Index score >25 and sclerotic tonsils. Being sensitive in 92.31%, specificity in 77.4% and positive likely hood ration of 4.00 and positive predictive value of 77.42%. The findings suggest tha.

ETIOLOGICAL SPECTRUM OF IRREVERSIBLE LOSS OF VISION IN TRIPOLI EYE HOSPITAL-LIBYA

Suleiman Younis Jai Elmdhm
ABSTRACT The study aimed to determine the causes of irreversible unilateral and bilateral severe visual loss that cannot be medically, optically or surgically rehabilitated, in patients followed at Tripoli Eye Hospital. A retrospective analysis was conducted on 43 patients with irreversible vision loss. Demographic and clinical data were collected, ocular diseases that could be treated, were excluded. Additionally, patients under 10 years of age were not included. The study showed unilateral irreversible vision loss (58%) were more prevalent than bilateral visual loss (41.8%). Male-to-female ratio was 2.07:1. Glaucoma was the most common cause (67.4%), followed by retinal diseases (21%). Primary open angle glaucoma was the predominant cause in the glaucoma group (51.7%), while tractional retinal detachment was the most common cause in the retinal group (44.4%), often associated with diabetes mellitus. Refractive amblyopia was the cause in all patients with refractive-related visual d.